How PEAs could help with chronic pain and inflammation.
We all know of peas, as this awesome tiny legume, versatile as ever, good source of protein, manganese, magnesium and potassium, they may also help and support good cardiovascular health, and quite high in polyphenols, C and E and zinc, and easy to prepare.
But PEAs – (palmitoylethanolamide) is totally different and is not related, but do contain minute traces in them. PEA’s to keep it short is actually an anti-neuroinflammatory compound and is a very similar substance to pharmacology effects of cannabinoids found in cannabis and belongs to a class of bio-active lipids NAE which also has been known for its strong ability to inhibit pain and inflammation.
PEA is an endogenously produced cannabimimetic compound and is why it is put in the same group as cannabinoids. It has been extensive in clinical trials and studies for its effect on:
- Analgesic effect on pain receptors
- Anti-inflammatory and neuroprotective effects
- Has shown positive effects on a range of conditions which includes, osteoarthritis, shingle pain, neuropathic pain, depression, autism, fibromyalgia, lower back pain and some autoimmune conditions.
- The compound has been found abundantly in the CNS (central nervous system) which is produced for neuron, immune cells, glial cells, and anti-neuroprotective pathways.
PEA was first found in 1957 and derived from soy lecithin, it has been even found to be used in the late 1930’s and was used and known to be sourced using dried egg yolk to children whom were exposed to poor nutritional status in this time and were found to be less rheumatic fever cases in these children, which was very much seen in many children in this period, and was most likely due to its very strong anti-inflammatory pathways and suppressing capabilities.
PEA can be found in food sources such as soy lecithin, breast milk, legumes, tomato, alfalfa, corn and peanuts.
PEA is a compound supplement that is worth considering for anyone who is looking for an alternative to pharmaceutical medications, and has no known side effects on contraindications.
For a Holistic management of pain, PEA being just one of nutritional support pathways for pain management and neuroprotective qualities, along with Bowen Therapy is an ideal alternative for anyone looking for pain relief .
As with most supplements it is important to seek professional natural health practitioner advice before taking most supplements.
- Artukoglu, B.B., Beyer, C., Zuloff-Shani, A., Brener, E. and Bloch, M.H., 2017. Efficacy of palmitoylethanolamide for pain: a meta-analysis. Pain physician, 20(5), pp.353-362.
- Petrosino, S. and Di Marzo, V., 2017. The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations. British journal of pharmacology, 174(11), pp.1349-1365.
- Ghafouri, N., Ghafouri, B., Larsson, B., Turkina, M.V., Karlsson, L., Fowler, C.J. and Gerdle, B., 2011. High levels of N-palmitoylethanolamide and N-stearoylethanolamide in microdialysate samples from myalgic trapezius muscle in women. PLoS One, 6(11), p.e27257.